Buffalo Grove Chiropractic Center

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Acetaminophen Toxicity
Borek C.  Antioxidant health effects of aged garlic extract.  J Nutr 2001;131:1010S-1015S.

Acetylcysteine (NAC)
Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Borek C.  Dietary antioxidants and human cancer.  Integ Cancer Therap 2004;3(4):333-341.

Buhl R, Meyer A, Vogelmeier C.  Oxidant-protease interaction in the lung: prospects for antioxidant therapy.  Chest 1996;110(6):267S-272S.

Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Jiang B, Haverty M, Brecher P.  N-acetyl-L-cysteine enhances interleukin-1B-induced nitric oxide synthase expression.  Hypertension 1999;34:574-579.

Kaneto H, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara Y, Hanafusa T, Matsuzawa Y, Yamasaki Y, Hori M.  Beneficial effects of antioxidants in diabetes.  Diabetes 1999;48:2398-2406.

Kowluru RA, Tang J, Kern TS.  Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII.  Effect of long-term administration of antioxidants on the development of retinopathy.  Diabetes 2001;50:1938-1942.

Lamson DW, Brignall MS.  Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.  Alt Med Rev 1999;4(5):304-329.

Logan AC, Wong C.  Chronic fatigue syndrome: oxidative stress and dietary modifications.  Altern Med Rev 2001;6(5):450-459.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Prasad KN.  Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity.  Integrat Cancer Therap 2004;3(4):310-322.

Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tspipursky, Nyland J.  Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (lutein antioxidant supplementation trial).  Optom 2004;75(4):216-230.

Vina J, Lloret A, Orti R, Alonso D.  Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress.  Mol Aspect Med 2004;25:117-123.

Tsuda H, Ohshima Y, Nomoto H, Fujita K, Matsuda E, Iigo M, Takasuka N, Moore MA.  Cancer prevention by natural compounds.  Drug Metab Pharmacokin 2004;19(4):245-263.

Acne
Barker J, Meletis CD.  Functional foods for childhood development.  Alt Comp Therap 2004;10(3):131-134.

Acquired Immunodeficiency Syndrome (AIDS)

Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Allard JP, Aghdassi E, Chau J, Salit I, Walmsley S.  Oxidative stress and plasma antioxidant micronutrients in humans with HIV.  Am J Clin Nutr 1998;67:143-147.

Fawzi WW, Msamanga G, Spiegelman D, Wei R, Kapiga S, Villamor E, Mwakagile D, Mugusi F, Hertzmark E, Essex M, Hunter DJ.  A randomized trial of multivitamin supplements and HIV disease progression and mortality.  N Engl J Med 2004;351:23-32.

Garcia de la Asuncion J, Del Olmo ML, Sastre J, Millain A, Pellin A, Pallardo FV.  AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria.  J Clin Invest 1998;102:4-9.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Rapport L, Lockwood B.  Proanthocyanidins and grape seed extract.  Pharm J 2001;266:581-584.

Vina J, Lloret A, Orti R, Alonso D.  Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress.  Mol Aspect Med 2004;25:117-123.

Acupuncture
Vickers AJ, Rees RW, Zollman CE, McCarney R, Smith C, Ellis N, Fisher P, Van Haselen R.  Acupuncture for chronic headache in primary care: large, pragmatic, randomised trial.  BMJ 2004; Online First:1-6.

Acute Lymphocytic Leukemia (ALL)
Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Papageorgiou M, Stiakaki E, Dimitriou H, Malliaraki N, Notas G, Castanas E, Kalmanti M.  Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies.  Leuk Res 2005;29:11-16.

Acute Myelogenous Leukemia (AML)
Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Lamson DW, Brignall MS.  Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.  Alt Med Rev 1999;4(5):304-329.

Papageorgiou M, Stiakaki E, Dimitriou H, Malliaraki N, Notas G, Castanas E, Kalmanti M.  Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies.  Leuk Res 2005;29:11-16.

Acute Respiratory Distress Syndrome (ARDS)
Fischer H, Schwarzer C, Illek B.  Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel.  Proc Natl Acad Sci USA 2004;101(10):3691-3696.

Kauwell GPA.  Emerging concepts in nutrigenomics: a preview of what is to come.  Nutr Clin Pract 2005;20(1):75-87.

Additive Allergy
Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Adenocarcinoma
Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Bhat KPL, Lantvit D, Christov K, Mehta RG, Moon RC, Pezzuto JM.  Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.  Cancer Res 2001;61:7456-7463.

Oliveira CPMS, Kassab P, Lopasso FP, Souza HP, Janiszewski M, Laurindo FRM, Iriya KI, Laudanna AA.  Protective effect of ascorbic acid in experimental gastric cancer: reduction of oxidative stress.  World J Gastroenterol 2003;9(3):446-448.

Rapport L, Lockwood B.  Proanthocyanidins and grape seed extract.  Pharm J 2001;266:581-584.

Adolescent
Barker J, Meletis CD.  Functional foods for childhood development.  Alt Comp Therap 2004;10(3):131-134.

Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Mannino ML, Lee Y, Mitchell DC, Smiciklas-Wright H, Birch LL.  The quality of girls' diets declines and tracks across middle childhood.  Int J Behav Nutr Phys Act 2004;1(5):1-11.

SanGiovanni JP, Chew EY.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.  Prog Retinal Eye Res 2005;24:87-138.

Aging
Adhami VM, Ahmad N, Mukhtar H.  Molecular targets for green tea in prostate cancer prevention.  J Nutr 2003;133:2417S-2424S.

Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Ames BN, Shigenaga MK, Hagen TM.  Oxidants, antioxidants, and the degenerative diseases of aging.  Proc Natl Acad Sci 1993;90:7915-7922.

Andres E, Loukili H, Noel E, Kaltenbach G, Abdelgheni MB, Perrin AE, Noblet-Dick M, Maloisel F, Schlienger JL, Blickle JF.  Vitamin B12 (cobalamin) deficiency in elderly patients.  CMAJ 2004;171(3):251-259.

Araghi-Niknam M, Hosseini S, Larson D, Rohdewald P, Watson RR.  Pine bark extract reduces platelet aggregation.  Int Med 1999;2:73-77.

Balducci L.  Anemia, cancer and aging.  Cancer Control 2003;10(6):478-486.

Berendshot TTJM, Goldbohm RA, Klopping WAA, van de Kraats J, van Norel J, van Norren D.  Influence of lutein supplementation on macular pigment, assessed with two objective techniques.  Invest Ophthalmol Vis Sci 2000;41:3322-3326.

Borek C.  Antioxidant health effects of aged garlic extract.  J Nutr 2001;131:1010S-1015S.

Borek C.  Dietary antioxidants and human cancer.  Integ Cancer Therap 2004;3(4):333-341.

Bsoul SA, Terezhalmy GT.  Vitamin C in health and disease.  J Contemp Dent Pract 2004;5(1):1-13.

Clarke R, Evans G, Schneede J, Nexo E, Bates E, Bates C, Fletcher A, Prentice A, Johnston C, Uleand PM, Refsum H, Sherliker P, Birks J, Whitlock G, Breeze E, Scott JM.  Vitamin B12 and folate deficiency in later life.  Age and Ageing 2004;33:34-41.

Corsini E, Lucchi L, Meroni M, Racchi M, Solerte B, Fioravanti M, Viviani B, Marinovich M, Govoni S, Galli CL.  In vivo dehydroepiandrosterone restores age-associated defects in the protein kinase C signal transduction pathway and related functional responses.  J Immunol 2002;168:1753-1758.

Droge W.  Free radicals in the physiological control of cell function.  Physiol Rev 2002;82:47-95.

Fernandez S, Mas R, Gamez R, Diaz A, Fernandez J, Orta SD, Illnait J, Castano G, Mendoza S, Valdes F, Alvarez E.  A pharmacological surveillance study of the tolerability of policosanol in the elderly population.  Am J Geriatr Pharmacother 2004;2:219-229.

Fine AM.  Oligomeric proanthocyanidin complexes:  history, structure, and phytopharmaceutical applications.  Alt Med Rev 2000;5(2):144-151.

Griffiths RD.  The evidence for glutamine use in the critically-ill.  Proc Nutr Soc 2001;60:403-410.

Harman D.  The aging process.  Proc Natl Acad Sci 1981;78(11):7124-7128.

Head KA. Isoflavones and other soy constituents in human health and disease.  Altern Med Rev 1997;2(6):433-450.

Heaton PR, Reed CF, Mann SJ, Ransley R, Stevenson J, Charlton CJ, Smith BHE, Harper EJ, Rawlings JM.  The role of dietary antioxidants to protect against DNA damage in adult dogs.  J Nutr 2002;132:1720S-1724S.

Joseph JA, Shukitt-Hale B, Denisova NA, Bielinkski D, Martin A, McEwen JJ, Bickford PC.  Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation.  J Neurosci 1999;19(18):8114-8121.

Klapcinska B, Derejczyk J, Wieczorowska-Tobis K, Sobczak A, Sadowska-Krepa E, Danch A.  Antioxidant defense in centenarians (a preliminary study).  Acta Bio Pol 2000;47(2):281-292.

Koo MWL, Cho CH.  Pharmacological effects of green tea on the gastrointestinal system.  Euro J Pharmacol 2004;500:177-185.

Leal-Cerro A, Povedano J, Astorga R, Gonzalez M, Silva H, Garcia-Pesquera F, Casanueva FF, Dieguez C.  The growth hormone (GH)-releasing hormone - GH - insulin-like growth factor-1 axis in patients with fibromyalgia syndrome.  J Clin Endocrinol Metab 1999;84:3378-3381.

MacKay D, Miller AL.  Nutritional support for wound healing.  Altern Med Rev 2003;8(4):359-377.

McPartland JM, Pruitt PL.  Benign prostatic hyperplasia treated with saw palmetto a literature search and an experimental case study.  JAOA 2000;100(2)89-96.

Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Neu J, DeMarco V, Li N.  Glutamine: clinical applications and mechanisms of action.  Curr Opin Clin Nutr Metab Care 2002;5:69-75.

Olivieri G, Otten U, Meier F, Baysang G, Dimitriades-Schmutz B, Muller-Spahn F, Savaskan E.  Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells.  Neurol Clinical Neurophysiol 2002;2:2-10.

Owens G, Balfour D, Biller BMK, Cohen J, Jacobs M, Lease M, Ratnesar R, Schaecher KL, Wilcox DE.  Clinical presentation and diagnosis: growth hormone deficiency in adults.  Am J Manage Care 2004;10(13):S424-S430.

Parle M, Dhingra D.  Ascorbic acid: a promising memory - enhancer in mice.  J Pharmacol Sci 2003;93:129-135.

Pierpaoli W, Regelson W.  Pineal control of aging:  effect of melatonin and pineal grafting on aging mice.  Proc Natl Acad Sci 1994;91:787-791.

Reynolds EH.  Folic acid, ageing, depression, and dementia.  Brit Med J 2002;324:1512-1515.

Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tspipursky, Nyland J.  Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (lutein antioxidant supplementation trial).  Optom 2004;75(4):216-230.

Ripple MO, Henry WF, Schwarze SR, Wilding G, Weindruch R.  Effect of antioxidants on androgen-induced AP-1 and NF-KB DNA-binding activity in prostate carcinoma cells.  J Natl Cancer Inst 1999;91:1227-1321.

Sanchez-Moreno C, Cao G, Ou B, Prior RL.  Anthocyanin and proanthocyanidin content in selected white and red wines.  Oxygen radical absorbance capacity comparison with nontraditional wines obtained from highbush blueberry.  J Agric Food Chem 2003;51:4889-4896.

SanGiovanni JP, Chew EY.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.  Prog Retinal Eye Res 2005;24:87-138.

Satoh H.  Comparative electropharmacological actions of some constituents from Ginkgo biloba extract in guinea-pig ventricular cardiomyocytes.  Evid Based Comp Altern Med 2004;1(3):277-284.

Sreemantula S, Nammi S, Kolanukonda R, Koppula S, Boini K.  Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model.  BMC Comp Alt Med 2005;5(1) doi:10.1186/1472-6882-5-1.

Shi J, Yu J, Pohorly JE, Kakuda Y.  Polyphyenolics in grape seeds - biochemistry and functionality.  J Med Food 2003;6(4):291-299.

Vina J, Lloret A, Orti R, Alonso D.  Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress.  Mol Aspect Med 2004;25:117-123.

Volterrani M, Giustina A, Manelli F, Cicoira MA, Lorusso R, Giordano A.  Role of growth hormone in chronic heart failure: therapeutic implications.  Ital Heart J 2000;1(11):732-738.

Waters DJ, Shen S, Cooley DM, Bostwick DG, Qian J, Combs GF, Glickman LT, Oteham C, Schlittler D, Morris JS.  Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate.  J Natl Cancer Inst 2004;95:237-241.

Watkins BA, Li Y, Lippman HE, Seifert MF.  Omega-3 polyunsaturated fatty acids and skeletal health.  Exp Biol Med 2001;226(6):485-497.

Yamada Y, Nakajima A, Sekihara H.  Anti-apoptotic effect of dehydroepiandrosterone and its role in an aging society.  Int Med 2004;43(2):158-160.

Alanine Aminotransferase (ALT)
Can A, Akev N, Ozsov N, Bolkent S, Arda BP, Yanardag R, Okyar A.  Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models.  Biol Pharm Bull 2004;27(5):694-698.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Yamada Y, Nakajima A, Sekihara H.  Anti-apoptotic effect of dehydroepiandrosterone and its role in an aging society.  Int Med 2004;43(2):158-160.

Alcoholism
Abascal K, Yarnell E.  The many faces of Silybum marianum (milk thistle), part 1 - treating cancer and hyperlipidemia and restoring kidney function.  Alt Comp Therapy 2003;9(4):170-175.

Abascal K, Yarnell E.  The many faces of Silybum marianum (milk thistle), part 2 - clinical uses, safety, and types of preparations.  Alt Comp Therapy 2003;9(5):251-257.

Chen A, Zhang L, Xu J and Tang J.  The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression.  Biochem J 2002;368:695-704.

Kerai MDJ, Waterfield CJ, Kenyon SH, Asker DS, Timbrell JA.  Reversal of ethanol-induced hepatic steatosis and lipid peroxidation by taurine: a study in rats.  Alcohol & Alcoholism 1999; 34(4):529-541.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Alfalfa
Cronin JR.  Comparing antioxidant values with the ORAC method.  Alt Comp Therap 2004;10(3):167-170.

Donaldson MS.  Nutrition and cancer: a review of the evidence for an anti-cancer diet.  Nutr J 2004;3:19 doi: 10.1186/1475-2891-3-19.

Allergy
Barker J, Meletis CD.  Functional foods for childhood development.  Alt Comp Therap 2004;10(3):131-134.

Fine AM.  Oligomeric proanthocyanidin complexes:  history, structure, and phytopharmaceutical applications.  Alt Med Rev 2000;5(2):144-151.

Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Ignatowicz E, Baer-Dubowska W.  Resveratrol, a natural chemopreventive agent against degenerative diseases.  Pol J Pharmacol 2001;53:557-569.

Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Ro JY, Lee BC, Kim JY, Chung YJ, Chung MH, Lee SK, Jo TH, Kim KH, Park YI.  Inhibitory mechanism of aloe single component (alprogren) on mediator release in guinea pig lung mast cells activated with specific antigen-antibody reactions.  J Pharmacol Exp Therap 2000;292(1):114-121.

Shah V, Bayeta E, Lau BHS.  Pycnogenol augments macrophage phagocytosis and cytokine secretion.  Pak J Nutr 2002;1(5):196-201.

Yamada Y, Nakajima A, Sekihara H.  Anti-apoptotic effect of dehydroepiandrosterone and its role in an aging society.  Int Med 2004;43(2):158-160.

Aloe barbadensis
Can A, Akev N, Ozsov N, Bolkent S, Arda BP, Yanardag R, Okyar A.  Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models.  Biol Pharm Bull 2004;27(5):694-698.

Ferro VA, Bradbhury F, Cameron P, Shakir E, Rahman SR, Stimson WH.  In vitro susceptibilities of Shigella flexneri and Streptococcus pyogenes to inner gel of Aloe barbadensis Miller.  Antimicrob Agents Chemother 2003;47(3):1137-1139.

Gupta R, Flora SJS.  Protective value of Aloe vera against some toxic effects of arsenic in rats.  Phytother Res 2005;1923-28.

Kim HS, Kacew S, Lee BM.  In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis Miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor).  Carcinogenesis 1999;20(8):1637-1640.

Kim HS, Lee BM.  Inhibition of benzo[a]pyrene-DNA adduct formation by Aloe barbadensis Miller.  Carcinogenesis 1997;18(4):771-776.

Rajasekaran S, Sivagnanam K, Subramanian S.  Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.  Pharmacol Rep 2005;57:90-96.

Aloe vera
Can A, Akev N, Ozsov N, Bolkent S, Arda BP, Yanardag R, Okyar A.  Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models.  Biol Pharm Bull 2004;27(5):694-698.

Gupta R, Flora SJS.  Protective value of Aloe vera against some toxic effects of arsenic in rats.  Phytother Res 2005;1923-28.

MacKay D, Miller AL.  Nutritional support for wound healing.  Altern Med Rev 2003;8(4):359-377.

Rajasekaran S, Sivagnanam K, Subramanian S.  Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.  Pharmacol Rep 2005;57:90-96.

Ro JY, Lee BC, Kim JY, Chung YJ, Chung MH, Lee SK, Jo TH, Kim KH, Park YI.  Inhibitory mechanism of aloe single component (alprogren) on mediator release in guinea pig lung mast cells activated with specific antigen-antibody reactions.  J Pharmacol Exp Therap 2000;292(1):114-121.

Syed TA, Ahmad SA, Holt AH, Ahmad SA, Ahmad SA, Afzai M.  Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study.  Trop Med Int Health 1996;1(4):505-509.

Wang ZW, Zhou JM, Huang ZS, Yang AP, Liu ZC, Xia YF, Zeng YX, Zhu XF.  Aloe polysaccharides mediated radioprotective effect through the inhibition of apoptosis.  J Radiat Res 2004;45:447-454.

Alpha-Ketoglutarate
Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Neu J, DeMarco V, Li N.  Glutamine: clinical applications and mechanisms of action.  Curr Opin Clin Nutr Metab Care 2002;5:69-75.

Alpha-Lipoic Acid
Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Konrad T, Vicini P, Kusterer K, Hoflich A, Assadkhani A, Bohles HJ, Sewell A, Tritschler HJ, Corbelli C, Usadel KH.  Alpha-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes.  Diabetes Care 1999;22:280-287.

Logan AC, Wong C.  Chronic fatigue syndrome: oxidative stress and dietary modifications.  Altern Med Rev 2001;6(5):450-459.

Midaoui AEL, de Champlain J.  Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid.  Hypertension 2002;39:303-307.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tspipursky, Nyland J.  Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (lutein antioxidant supplementation trial).  Optom 2004;75(4):216-230.

Saengsirisuwan V, Kinnick TR, Schmit MB, Henriksen EJ.  Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats.  J Appl Physiol 2001;91:145-153.

Alzheimer Disease
Andres E, Loukili H, Noel E, Kaltenbach G, Abdelgheni MB, Perrin AE, Noblet-Dick M, Maloisel F, Schlienger JL, Blickle JF.  Vitamin B12 (cobalamin) deficiency in elderly patients.  CMAJ 2004;171(3):251-259.

Borek C.  Antioxidant health effects of aged garlic extract.  J Nutr 2001;131:1010S-1015S.

Bourdel-Marchasson I, Delmas-Beauvieux MC, Peuchant E, Richard-Harston S, Decamps A, Reignier B, Emeriau JP, Rainfray M.  Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients.  Age and Ageing 2001;30:235-241.

Bsoul SA, Terezhalmy GT.  Vitamin C in health and disease.  J Contemp Dent Pract 2004;5(1):1-13.

Christen, Y.  Oxidative stress and Alzheimer disease.  Am J Clin Nutr 2000; (suppl):621S-9S.

Gao J, Sun HY, Zhu ZR, Ding Z, Zhu L.  Antioxidant effects of dehydroepiandrosterone are related to up-regulation of thioredoxin in SH-SY5Y cells.  Acta Biochimica et Biophysica Sinica 2005;37(2):119-125.

Klein JA, Ackerman SL.  Oxidative stress, cell cycle, and neurodegneration.  J Clin Invest 2003;111:785-793.

Grundman M.  Vitamin E and Alzheimer disease: the basis for additional trials.  Am J Clin Nutr 2000;71(suppl):630S-636S.

Klein JA, Ackerman SL.  Oxidative stress, cell cycle, and neurodegneration.  J Clin Invest 2003;111:785-793.

Luo Y, Smith JV, Paramasivam V, Burdick A, Curry KJ, Buford JP, Khan I, Netzer WJ, Xu H, Butko P.  Inhibition of amyloid-B aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761.  Proc Natl Acad Sci 2002;99(19)12197-12202.

Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Nourhashemi F, Gillette-Guyonnet S, Andrieu S, Ghisolfi A, Ousset PJ, Grandjean H, Grand A, Pous J, Vellas B, Albarede JL.  Alzheimer disease: protective factors.  Am J Clin Nutr 2000;71(suppl):643S-649S.

Olivieri G, Otten U, Meier F, Baysang G, Dimitriades-Schmutz B, Muller-Spahn F, Savaskan E.  Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells.  Neurol Clinical Neurophysiol 2002;2:2-10.

Parle M, Dhingra D.  Ascorbic acid: a promising memory - enhancer in mice.  J Pharmacol Sci 2003;93:129-135.

Reiter RJ.  Melatonin: lowering the high price of free radicals.  News Physiol Sci 2000;15:246-250.

Reynolds EH.  Folic acid, ageing, depression, and dementia.  Brit Med J 2002;324:1512-1515.

SanGiovanni JP, Chew EY.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.  Prog Retinal Eye Res 2005;24:87-138.

Skaper SD, Ancona B, Facci L, Franceschini D, Giusti P.  Melatonin prevent the delayed death of hippocampal neurons induced by enhanced excitatory neurotransmission and the nitridergic pathway.  FASEB J 1998;12:725-731.

Sreemantula S, Nammi S, Kolanukonda R, Koppula S, Boini K.  Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model.  BMC Comp Alt Med 2005;5(1) doi:10.1186/1472-6882-5-1.

Vina J, Lloret A, Orti R, Alonso D.  Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress.  Mol Aspect Med 2004;25:117-123.

American Ginseng
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Amino Acid
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Kaput J, Rodriquez RL.  Nutritional genomics: the next frontier in the postgenomic era.  Physiol Genomics 2004;16:166-177.

Neu J, DeMarco V, Li N.  Glutamine: clinical applications and mechanisms of action.  Curr Opin Clin Nutr Metab Care 2002;5:69-75.

Amphetamine
Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Amyloidosis
Andres E, Loukili H, Noel E, Kaltenbach G, Abdelgheni MB, Perrin AE, Noblet-Dick M, Maloisel F, Schlienger JL, Blickle JF.  Vitamin B12 (cobalamin) deficiency in elderly patients.  CMAJ 2004;171(3):251-259.

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Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
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Matthews RT, Yang L, Browne S, Baik M, Beal MF.  Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects.  Proc Natl Acad Sci 1998;95:8892-8897.

Analgesia
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Hostanska K, Nisslein T, Freudenstein F, Reichling J, Saller R.  Evaluation of cell death caused by triterpene glycosides and phenolic substances from Cimicifuga racemosa extract in human MCF-7 breast cancer cells.  Biol Pharm Bull 2004;27(12):1970-1975.

Anemia
Andres E, Loukili H, Noel E, Kaltenbach G, Abdelgheni MB, Perrin AE, Noblet-Dick M, Maloisel F, Schlienger JL, Blickle JF.  Vitamin B12 (cobalamin) deficiency in elderly patients.  CMAJ 2004;171(3):251-259.

Balducci L.  Anemia, cancer and aging.  Cancer Control 2003;10(6):478-486.

Bsoul SA, Terezhalmy GT.  Vitamin C in health and disease.  J Contemp Dent Pract 2004;5(1):1-13.

Clarke R, Evans G, Schneede J, Nexo E, Bates E, Bates C, Fletcher A, Prentice A, Johnston C, Uleand PM, Refsum H, Sherliker P, Birks J, Whitlock G, Breeze E, Scott JM.  Vitamin B12 and folate deficiency in later life.  Age and Ageing 2004;33:34-41.

Pittock SJ, Payne TA, Harper CM.  Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency.  Mayo Clin Proc 2002;77:291-294.

Reynolds EH.  Folic acid, ageing, depression, and dementia.  Brit Med J 2002;324:1512-1515.

Angina Pectoris
Chang Q, Zuo Z, Harrison F, Sum Chow MS.  Hawthorn.  J Clin Pharmacol 2002;42:605-612.

Angiogenesis
Adhami VM, Ahmad N, Mukhtar H.  Molecular targets for green tea in prostate cancer prevention.  J Nutr 2003;133:2417S-2424S.

Agarwal C, Singh RP, Dhanalaksmi S, Agarwal R.  Anti-angiogenic efficacy of grape seed extract in endothelial cells.  Oncol Rep 2004;11:681-685.

Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Aziz MA, Kumar R, Ahmad.  Cancer chemoprevention by resveratrol:  in vitro and in vivo studies and the underlying mechanisms (review).  Int J Oncol 2003;23:17-28.

Borek C.  Dietary antioxidants and human cancer.  Integ Cancer Therap 2004;3(4):333-341.

Head KA. Isoflavones and other soy constituents in human health and disease.  Altern Med Rev 1997;2(6):433-450.

Koo MWL, Cho CH.  Pharmacological effects of green tea on the gastrointestinal system.  Euro J Pharmacol 2004;500:177-185.

Miyazawa T, Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M.  Anti-angiogenic potential of tocotrienol in vitro.  Biochem (Moscow) 2004;69(1):85-88.

Oak MH, El Bedoui J, Schini-Kerth BV.  Antiangiogenic properties of natural polyphenols from red wine and green tea.  J Nutr Biochem 2005;16:1-8.

Prasad KN.  Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity.  Integrat Cancer Therap 2004;3(4):310-322.

SanGiovanni JP, Chew EY.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.  Prog Retinal Eye Res 2005;24:87-138.

Singh R, Tyagi AK, Dhanalakshmi S, Agarwal R, Agarwal C.  Grape seed extract inhibits human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.  Int J Cancer 2004;108:733-740.

Tsuda H, Ohshima Y, Nomoto H, Fujita K, Matsuda E, Iigo M, Takasuka N, Moore MA.  Cancer prevention by natural compounds.  Drug Metab Pharmacokin 2004;19(4):245-263.

Angiotensin-Converting Enzyme (ACE)
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Anorexia
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Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Anoxia
Satoh H.  Comparative electropharmacological actions of some constituents from Ginkgo biloba extract in guinea-pig ventricular cardiomyocytes.  Evid Based Comp Altern Med 2004;1(3):277-284.

Anthocyanin
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Kay CD, Holub BJ.  The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects.  Brit J Nutr 2002;88:389-397.

Mongraph.  Vaccinium myrtillus (bilberry).  Alt Med Rev 2001;6(1):500-504.

Rapport L, Lockwood B.  Proanthocyanidins and grape seed extract.  Pharm J 2001;266:581-584.

Sanchez-Moreno C, Cao G, Ou B, Prior RL.  Anthocyanin and proanthocyanidin content in selected white and red wines.  Oxygen radical absorbance capacity comparison with nontraditional wines obtained from highbush blueberry.  J Agric Food Chem 2003;51:4889-4896.

Tsuda H, Ohshima Y, Nomoto H, Fujita K, Matsuda E, Iigo M, Takasuka N, Moore MA.  Cancer prevention by natural compounds.  Drug Metab Pharmacokin 2004;19(4):245-263.

Antibiotic
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Sullivan A, Ford CE.  Probiotics in human infections.  J Antimicrobial Chemotherapy 2002;50:625-627.

Antioxidant
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Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Allard JP, Aghdassi E, Chau J, Salit I, Walmsley S.  Oxidative stress and plasma antioxidant micronutrients in humans with HIV.  Am J Clin Nutr 1998;67:143-147.

Ambrosone CB, Freudenheim JL, Thompson PA, Bowman E, Vena JE, Marshall JR, Graham S, Laughlin R, Nemoto T, Shields PG.  Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer.  Cancer Res 1999;59:602-606.

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Araghi-Niknam M, Hosseini S, Larson D, Rohdewald P, Watson RR.  Pine bark extract reduces platelet aggregation.  Int Med 1999;2:73-77.

Aziz MA, Kumar R, Ahmad.  Cancer chemoprevention by resveratrol:  in vitro and in vivo studies and the underlying mechanisms (review).  Int J Oncol 2003;23:17-28.

Barnard RJ.  Prevention of cancer through lifestyle changes.  eCAM 2004;1(3):233-239.

Bhathena SJ, Velasquez MT.  Beneficial role of dietary phytoestrogens in obesity and diabetes.  Am J Clin Nutr 2002;76:1191-1201.

Borek C.  Antioxidant health effects of aged garlic extract.  J Nutr 2001;131:1010S-1015S.

Borek C.  Dietary antioxidants and human cancer.  Integ Cancer Therap 2004;3(4):333-341.

Bourdel-Marchasson I, Delmas-Beauvieux MC, Peuchant E, Richard-Harston S, Decamps A, Reignier B, Emeriau JP, Rainfray M.  Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients.  Age and Ageing 2001;30:235-241.

Brignardello E, Gallo M, Aragno M, Manti R, Tamagno E, Danni O, Boccuzzi G.  Dehydroepiandrosterone prevents lipid peroxidation and cell growth inhibition by high glucose concentration in cultured rat mesangial cells.  J Endrocrinol 2000;166:401-406.

Brown NS, Bicknell R.  Hypoxia and oxidative stress in breast cancer, oxidative stress:  its stress on the growth, metastatic potential and response to therapy of breast cancer.  Breast Cancer Res 2001;3:323-327.

Bruce B, Spiller GA, Klevay LM, Gallagher SK.  A diet high in whole and unrefined foods favorably alters antioxidant defenses and colon function.  J Am Col Nutr 2000;19(1):61-67.

Bsoul SA, Terezhalmy GT.  Vitamin C in health and disease.  J Contemp Dent Pract 2004;5(1):1-13.

Chen A, Zhang L, Xu J and Tang J.  The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression.  Biochem J 2002;368:695-704.

Claustrat B, Brun J, Chazot G.  The basic physiology and pathophysiology of melatonin.  Sleep Med 2005;9:11-24.

Dixon RA, Xie DY, Sharma SB.  Proanthocyanidins - a final frontier in flavonoid research? New Phytol 2005;165:9-28.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Buhl R, Meyer A, Vogelmeier C.  Oxidant-protease interaction in the lung: prospects for antioxidant therapy.  Chest 1996;110(6):267S-272S.

Can A, Akev N, Ozsov N, Bolkent S, Arda BP, Yanardag R, Okyar A.  Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models.  Biol Pharm Bull 2004;27(5):694-698.

Chang Q, Zuo Z, Harrison F, Sum Chow MS.  Hawthorn.  J Clin Pharmacol 2002;42:605-612.

Chen SS, Chang LS, Chen HW, Wei YH.  Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele.  Hum Reprod 2002;17(3):718-725.

Chistyakov DA, Savost'anov KV, Zotova EV, Nosikov VV.  Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus.  BMC Med Genet 2001;2:4.

Clifton PM.  Effect of grape seed extract and quercetin on cardiovascular and endothelial parameters in high-risk subjects.  J Biomed Biotech 2004;5:272-278.

Correa P, Fontham ETH, Bravo JC, Bravo LE, Ruiz B, Zarama G, Realpe JL, Malcolm GT, Li D, Johnson WD, Mera R.  Chemoprevention of gastric dysplasia: randomized trial of antioxidants and anti-Helicobacter pylori therapy.  J Natl Cancer Inst 2000;92(23):1881-1888.

Cronin JR.  Comparing antioxidant values with the ORAC method.  Alt Comp Therap 2004;10(3):167-170.

Cuzzocrea S, Riley DP, Riley DP, Caputi AP, Salvemini D.  Antioxidant therapy:  a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury.  Pharm Rev 2001;53:135-159.

Dieber-Rotheneder M, Puhl H, Waeg G, Striegl G, Esterbauer H.  Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.  J Lipid Res 1991;32:1325-1332.

Di Paola R, Mazzon E, Muia C, Genovese T, Menegazzi M, Zaffini R, Suzuki H, Cuzzocrea S.  Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.  Resp Res 2005,6:66 doi:10.1186/1465-9921-6-66.

Donaldson MS.  Nutrition and cancer: a review of the evidence for an anti-cancer diet.  Nutr J 2004;3:19 doi: 10.1186/1475-2891-3-19.

Droge W.  Free radicals in the physiological control of cell function.  Physiol Rev 2002;82:47-95.

Du WD, Yuan ZR, Sun J, Tang JX, Cheng AQ, Shen DM, Huang CJ, Song XH, Yu XF, Zheng SB.  Therapeutic efficacy of high-dose vitamin C on acute pancreatitis and its potential mechanisms.  World J Gastroenterol 2003;9(11):2565-2569.

Eastwood MA.  Interaction of dietary antioxidants in vivo: how fruit and vegetables prevent disease?  Q J Med 1999;92:527-530.

Farre AL, Casado S.  Heart failure, redox alterations, and endothelial dysfunction.  Hypertension 2001;38:1400-1405.

Fawzi WW, Msamanga G, Spiegelman D, Wei R, Kapiga S, Villamor E, Mwakagile D, Mugusi F, Hertzmark E, Essex M, Hunter DJ.  A randomized trial of multivitamin supplements and HIV disease progression and mortality.  N Engl J Med 2004;351:23-32.

Fine AM.  Oligomeric proanthocyanidin complexes:  history, structure, and phytopharmaceutical applications.  Alt Med Rev 2000;5(2):144-151.

Fischer H, Schwarzer C, Illek B.  Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel.  Proc Natl Acad Sci USA 2004;101(10):3691-3696.

Basu S, Riserus U, Turpeinen A, Vessby B.  Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity.  Clin Sci 2000;99:511-516.

Gao J, Sun HY, Zhu ZR, Ding Z, Zhu L.  Antioxidant effects of dehydroepiandrosterone are related to up-regulation of thioredoxin in SH-SY5Y cells.  Acta Biochimica et Biophysica Sinica 2005;37(2):119-125.

Garcia de la Asuncion J, Del Olmo ML, Sastre J, Millain A, Pellin A, Pallardo FV.  AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria.  J Clin Invest 1998;102:4-9.

Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC.  Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar B-adrenergic function and increases in proinflammatory cytokines.  Soc Neurosci 2002;22(14):6114-6120.

Gilgun-Sherki, Rosenbaum Z, Melamed E, Offen D.  Antioxidant therapy in acute central nervous system injury: current state.  Pharmacol Rev 2002;54:271-284.

Griffin JL, Muller D, Woograsingh R, Jowatt V, Hindmarsh A, Nicholson JK, Martin JE.  Vitamin E deficiency and metabolic deficits in neuronal ceroid lipofuscinosis described by bioinformatics.  Physiol Genomics 2002;11:195-2003.

Gulati OP.  Pycnogenol in venous disorders: a review.  Europ Bull Drug Res 1999;7(2):1-6.

Gupta R, Flora SJS.  Protective value of Aloe vera against some toxic effects of arsenic in rats.  Phytother Res 2005;1923-28.

Hanna J, Chahine R, Aftimas G, Nader G, Nader M, Mounayer A, Esseily F, Chamat S.  Protective effect of taurine against free radicals damage in the rat myocardium.  Exp Toxic Pathol 2004;56:189-194.

Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Harman D.  The aging process.  Proc Natl Acad Sci 1981;78(11):7124-7128.

Head KA. Isoflavones and other soy constituents in human health and disease.  Altern Med Rev 1997;2(6):433-450.

Heaney AP, Sharer N, Rameh B, Braganza JM, Durrington PN.  Prevention of recurrent pancreatitis in familial lipoprotein lipase deficiency with high-dose antioxidant therapy.  J Clin Endocrinol Metab 1999;84:1203-1205.

Heaton PR, Reed CF, Mann SJ, Ransley R, Stevenson J, Charlton CJ, Smith BHE, Harper EJ, Rawlings JM.  The role of dietary antioxidants to protect against DNA damage in adult dogs.  J Nutr 2002;132:1720S-1724S.

Ignatowicz E, Baer-Dubowska W.  Resveratrol, a natural chemopreventive agent against degenerative diseases.  Pol J Pharmacol 2001;53:557-569.

Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM.  Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.  Science 1997;275:218-220.

Janikula M.  Policosanol: a new treatment for cardiovascular disease? Alt Med Rev 2002;7(3):203-217.

Ji YC, Kim YB, Park SW, Hwang SN, Min BK, Hong HJ, Kwon JT, Suk JS.  Neuroprotective effect of ginseng total saponins in experimental traumatic brain injury.  J Korean Med Sci 2005;20:291-296.

Jiangang Z, Yuanzhu H, Qi C, Enhui W, Kejiang C, Wu J.  Effects of resveratrol on oxidative modification of human low density lipoprotein.  Chin Med J 2000;113(2):99-102.

Joseph JA, Shukitt-Hale B, Denisova NA, Bielinkski D, Martin A, McEwen JJ, Bickford PC.  Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation.  J Neurosci 1999;19(18):8114-8121.

Kagan VE, Yalowich JC, Borisenko GG, Tyurina YY, Tyurin V, Thampatty P, Fabisiak JP.  Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia:  free radical/antioxidant approach.  Mol Pharm 1999;56:494-506.

Kaneto H, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara Y, Hanafusa T, Matsuzawa Y, Yamasaki Y, Hori M.  Beneficial effects of antioxidants in diabetes.  Diabetes 1999;48:2398-2406.

Kang JS, Jeon YJ, Park SK, Yang KH, Kim HM.  Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1B and prostaglandin E2 synthesis by silymarin.  Biochem Pharacol 2004;67:175-181.

Kay CD, Holub BJ.  The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects.  Brit J Nutr 2002;88:389-397.

Keck AS, Finley JW.  Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.  Integ Cancer Therap 2004;3(1):5-12.

Kidd PM.  Multiple sclerosis, an autoimmune inflammatory disease: prospects for its integrative management.  Altern Med Rev 2001;6(6):540-566.

Kim YJ, Park HJ, Yoon SH, Kim MJ, Leem KH, Chung JH, Kim HK.  Anticancer effects of oligomeric proanthocyanidins on human colorectal cancer cell line, SNU-C4.  World J Gastroenterol 2005;11(30):4674-4678.

Klapcinska B, Derejczyk J, Wieczorowska-Tobis K, Sobczak A, Sadowska-Krepa E, Danch A.  Antioxidant defense in centenarians (a preliminary study).  Acta Bio Pol 2000;47(2):281-292.

Klein JA, Ackerman SL.  Oxidative stress, cell cycle, and neurodegneration.  J Clin Invest 2003;111:785-793.

Konowalchuk J, Speirs JI.  Virus inactivation by grapes and wines.  Appl Environ Microbiol 1976;32(6):757-763.

Konrad T, Vicini P, Kusterer K, Hoflich A, Assadkhani A, Bohles HJ, Sewell A, Tritschler HJ, Corbelli C, Usadel KH.  Alpha-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes.  Diabetes Care 1999;22:280-287.

Koo MWL, Cho CH.  Pharmacological effects of green tea on the gastrointestinal system.  Euro J Pharmacol 2004;500:177-185.

Kowluru RA, Tang J, Kern TS.  Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII.  Effect of long-term administration of antioxidants on the development of retinopathy.  Diabetes 2001;50:1938-1942.

Kucharska J, Govozdjakova A, Mizera S, Braunova Z, Schreinerova Z, Schramekova E, Pechan I, Fabian J.  Participation of coenzyme q10 in the rejection development of the transplanted heart: a clinical study.  Physiol Res 1998;47:399-404.

Lahiri-Chatterjee M, Katiyar SK, Mohan RR, Agarwal R.  A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model.  Cancer Res 1999;59:622-632.

Lamson DW, Brignall MS.  Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.  Alt Med Rev 1999;4(5):304-329.

Lerner V, Miodownik C, Kaptsan A, Cohen H, Matar M, Loewenthal U, Kotler M.  Vitamin B6 in the treatment of tardive dyskinesia: a double blind, placebo-controlled, crossover study.  Am J Psychiatry 2001;158:1511-1514.

Lewis GRJ.  Should doctors discourage nutritional supplementation? A cardiovascular approach.  Heart Lung Circ 2004;13:245-251.

Lin JK, Tsai SH.  Chemoprevention of cancer and cardiovascular disease by resveratrol.  Proc Natl Sci Counc 1999;23(3):99-106.

Liu D, Wen J, Liu J, Li L.  The roles of free radicals in amyotrophic lateral sclerosis:  reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids.  FASEB 1999;13:2318-2328.

Liu X, Wei J, Tan F, Zhou S, Wurthwein G, Rohdewald P.  Pycnogenol, french maritime pine bark extract, improves endothelial function of hypertensive patients.  Life Sci 2004;74:855-862.

Logan AC, Wong C.  Chronic fatigue syndrome: oxidative stress and dietary modifications.  Altern Med Rev 2001;6(5):450-459.

MacKay D, Miller AL.  Nutritional support for wound healing.  Altern Med Rev 2003;8(4):359-377.

Midaoui AEL, de Champlain J.  Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid.  Hypertension 2002;39:303-307.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Miyazawa T, Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M.  Anti-angiogenic potential of tocotrienol in vitro.  Biochem (Moscow) 2004;69(1):85-88.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Mongraph.  Vaccinium myrtillus (bilberry).  Alt Med Rev 2001;6(1):500-504.

Montonen J, Knekt P, Jarvinen R, Reunanen A.  Dietary antioxidant intake and risk of type 2 diabetes.  Diabetes Care 2004;27:362-366.

Nakamura Y, Tonogai Y.  Effects of grape seed polyphenols on serum and hepatic lipid contents and fecal steroid excretion in normal and hypercholesterolemic rats.  J Health Sci 2002;48(6):570-578.

Nourhashemi F, Gillette-Guyonnet S, Andrieu S, Ghisolfi A, Ousset PJ, Grandjean H, Grand A, Pous J, Vellas B, Albarede JL.  Alzheimer disease: protective factors.  Am J Clin Nutr 2000;71(suppl):643S-649S.

Nuttall SL, Kendall MJ, Martin U.  Antioxidant therapy for the prevention of cardiovascular disease.  Q J Med 1999;92:239-244.

Oak MH, El Bedoui J, Schini-Kerth BV.  Antiangiogenic properties of natural polyphenols from red wine and green tea.  J Nutr Biochem 2005;16:1-8.

O'Connell BS.  Select vitamins and minerals in the management of diabetes.  Diabetes Spectrum 2001;14(3):133-148.

O'Donovan DJ, Fernandes CJ.  Free radicals and diseases in premature infants.  Antioxid Redox Signal 2004;6(1):169-176.

Oliveira CPMS, Kassab P, Lopasso FP, Souza HP, Janiszewski M, Laurindo FRM, Iriya KI, Laudanna AA.  Protective effect of ascorbic acid in experimental gastric cancer: reduction of oxidative stress.  World J Gastroenterol 2003;9(3):446-448.

Olivieri G, Otten U, Meier F, Baysang G, Dimitriades-Schmutz B, Muller-Spahn F, Savaskan E.  Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells.  Neurol Clinical Neurophysiol 2002;2:2-10.

Papageorgiou M, Stiakaki E, Dimitriou H, Malliaraki N, Notas G, Castanas E, Kalmanti M.  Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies.  Leuk Res 2005;29:11-16.

Parle M, Dhingra D.  Ascorbic acid: a promising memory - enhancer in mice.  J Pharmacol Sci 2003;93:129-135.

Peterhans E.  Oxidants and antioxidants in viral diseases: disease mechanisms and metabolic regulation.  J Nutr 1997;127:962S-965S.

Pinent M, Blay M. Blade MC, Salvado MJ, Arola L, Ardevol A.  Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines.  Endocrinol 2004;10.1210/en.2004-0764.

Prasad KN.  Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity.  Integrat Cancer Therap 2004;3(4):310-322.

Prasad KN, Cole WC, Kumar B.  Multiple antioxidants in the prevention and treatment of Parkinson's disease.  J Amer Col Nutr 1999; 18(5):413-423.

Prasad KN, Cole WC, Kumar B, Prasad KC.  Scientific rationale for using high-dose multiple micronutrients as an adjunct to standard and experimental cancer therapies.  J Amer Coll Nutr 2001;20(5):450S-463S.

Prasad KN, Kumar A, Kochupillai V, Cole WC.  High doses of multiple antioxidant vitamins: essential ingredients in improving the efficacy of standard cancer therapy.  J Am Coll Nutr 1999: 18(1):13-25.

Rahman I, MacNee W.  Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease.  Am J Physiol Lung Cell Mol Physiol 1999;277(6):L1067-L1088.

Rajasekaran S, Sivagnanam K, Subramanian S.  Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.  Pharmacol Rep 2005;57:90-96.

Rapport L, Lockwood B.  Proanthocyanidins and grape seed extract.  Pharm J 2001;266:581-584.

Reiter RJ.  Melatonin: lowering the high price of free radicals.  News Physiol Sci 2000;15:246-250.

Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tspipursky, Nyland J.  Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (lutein antioxidant supplementation trial).  Optom 2004;75(4):216-230.

Ripple MO, Henry WF, Schwarze SR, Wilding G, Weindruch R.  Effect of antioxidants on androgen-induced AP-1 and NF-KB DNA-binding activity in prostate carcinoma cells.  J Natl Cancer Inst 1999;91:1227-1321.

Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, Tellez-Rojo MM, Moreno-Macias HM, Reyes-Ruiz NL, del Rio-Navarro BE, Ruiz-Navarro MX, Hatch G, Slade R, Hernandez-Avila M.  Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants.  Am J Respir Crit Care Med 2002;166:703-709.

Roseff SJ, Gulati R.  Improvement of sperm quality by pycnogenol.  Europ Bull Drug Res 1999;7(2):1-4.

Saengsirisuwan V, Kinnick TR, Schmit MB, Henriksen EJ.  Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats.  J Appl Physiol 2001;91:145-153.

Saito M, Satoh S, Kojima N, Tada H, Sato M, Suzuki T, Senoo H, Habuchi T.  Effects of a phenolic compound, resveratrol, on the renal function and costimulatory adhesion molecule CD86 experession in rat kidneys with ischemia/reperfusion injury.  Arch Histol Cytol 2005;68(1):41-49.

Sanchez-Moreno C, Cao G, Ou B, Prior RL.  Anthocyanin and proanthocyanidin content in selected white and red wines.  Oxygen radical absorbance capacity comparison with nontraditional wines obtained from highbush blueberry.  J Agric Food Chem 2003;51:4889-4896.

SanGiovanni JP, Chew EY.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.  Prog Retinal Eye Res 2005;24:87-138.

Sano T, Oda E, Yamashita T, Naemura A, Ijiri Y, Yamakoshi J, Yamamoto J.  Anti-thrombotic effect of proanthocyanidin, a purified ingredient of grape seed.  Throm Res 2005;115:115-121.

Satoh H.  Comparative electropharmacological actions of some constituents from Ginkgo biloba extract in guinea-pig ventricular cardiomyocytes.  Evid Based Comp Altern Med 2004;1(3):277-284.

Shacter E, Williams JA, Hinson RM, Senturker S, Lee YY.  Oxidative stress interferes with cancer chemotherapy: inhibition of lymphoma cell apoptosis and phagocytosis.  Blood 2000;96(1):307-313.

Shah V, Bayeta E, Lau BHS.  Pycnogenol augments macrophage phagocytosis and cytokine secretion.  Pak J Nutr 2002;1(5):196-201.

Shaheen SO, Sterne JAC, Thompson RL, Songhurst CE, Margetts BM, Burney PGJ.  Dietary antioxidants and asthma in adults.  Am J Respir Crit Care Med 2001;164:1823-1828.

Shi J, Yu J, Pohorly JE, Kakuda Y.  Polyphyenolics in grape seeds - biochemistry and functionality.  J Med Food 2003;6(4):291-299.

Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP, Jockusch SS, Itagaki Y, Nakanishi K.  A2E-expoxides damage DNA in retinal pigment epithelial cells: vitamin E and other antioxidants inhibit A2E-epoxide formation.  J Biol Chem 2003;278(20):18207-18213.

Sreemantula S, Nammi S, Kolanukonda R, Koppula S, Boini K.  Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model.  BMC Comp Alt Med 2005;5(1) doi:10.1186/1472-6882-5-1.

Szende B, Tyihak E, Kiraly-Veghely Z.  Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures.  Exp Mol Med 2000;32(2):88-92.

Thomas SR, Leichtweis SB, Pettersson K, Croft KD, Mori TA, Brown AJ, Stocker R.  Dietary cosupplementation with vitamin E and coenzyme Q10 inhibits atherosclerosis in apolipoprotein E gene knockout mice.  Arterioscler Thromb Vasc Biol 2001;21:583-593.

Tomasetti M, Alleva R, Borghi B, Collins AR.  In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage.  FASEB J 2001;15(8):1425-1427.

Tozzi G, Nuccetelli M, Lo Bello M, Bernadrdini S, Bellincampi L, Ballerini S, Gaeta LM, Casali C, Pastore A, Federici G, Bertini E, Piemonte F.  Antioxidant enzymes in blood of patients with Friedreich's ataxia.  Arch Dis Child 2002;86:376-380.

Tsuchiya M, Asada A, Kasahara E, Sato EF, Shindo M, Inoue M.  Smoking a single cigarette rapidly reduces combined concentrations of nitrate and nitrite and concentrations of antioxidants in plasma.  Circulation 2002;105:1155-1157.

Tsuda H, Ohshima Y, Nomoto H, Fujita K, Matsuda E, Iigo M, Takasuka N, Moore MA.  Cancer prevention by natural compounds.  Drug Metab Pharmacokin 2004;19(4):245-263.

Velsor LW, Van Heeckeren A, Day BJ.  Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice.  Am J Physiol Lung Cell Mol Physiol 2001;281:L31-L38.

Vina J, Lloret A, Orti R, Alonso D.  Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress.  Mol Aspect Med 2004;25:117-123.

Waters DJ, Shen S, Cooley DM, Bostwick DG, Qian J, Combs GF, Glickman LT, Oteham C, Schlittler D, Morris JS.  Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate.  J Natl Cancer Inst 2004;95:237-241.

Watson RR.  Pycnogenol and cardiovascular health.  Evidence-Based Integ Med 2003;1(1):27-32.

Weng-Guang L, Xiao-Yu Z, Yong-Jie W, Xuan T.  Anti-inflammatory effect and mechanism of proanthocyanidins from grape seeds.  Acta Pharmacol Sin 2001;12:1117-1120

Yang YB, Piao YJ.  Effects of resveratrol on secondary damages after acute spinal cord injury in rats.  Acta Pharmacol Sin 2003;24(7):703-710.

Zapatero JM.  Selections from current literature: effects of Hawthorn on the cardiovascular system.  Fam Pract 1999;16(5):534-538.

Antiretroviral Therapy
Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Fawzi WW, Msamanga G, Spiegelman D, Wei R, Kapiga S, Villamor E, Mwakagile D, Mugusi F, Hertzmark E, Essex M, Hunter DJ.  A randomized trial of multivitamin supplements and HIV disease progression and mortality.  N Engl J Med 2004;351:23-32.

Anxiety
Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Apoptosis
Adhami VM, Ahmad N, Mukhtar H.  Molecular targets for green tea in prostate cancer prevention.  J Nutr 2003;133:2417S-2424S.

Agarwal C, Singh RP, Dhanalaksmi S, Agarwal R.  Anti-angiogenic efficacy of grape seed extract in endothelial cells.  Oncol Rep 2004;11:681-685.

Agarwal C, Singh RP, Agarwal R.  Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release.  Carcinogenesis 2002;23(11):1869-1876.

Aggarwal BB, Bhardwa A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y.  Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.  Anticancer Res 2004;24(5A):2783-2841.

Aziz MA, Kumar R, Ahmad.  Cancer chemoprevention by resveratrol:  in vitro and in vivo studies and the underlying mechanisms (review).  Int J Oncol 2003;23:17-28.

Bhat KPL, Lantvit D, Christov K, Mehta RG, Moon RC, Pezzuto JM.  Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.  Cancer Res 2001;61:7456-7463.

Borek C.  Dietary antioxidants and human cancer.  Integ Cancer Therap 2004;3(4):333-341.

Chen A, Zhang L, Xu J and Tang J.  The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression.  Biochem J 2002;368:695-704.

Dixon RA, Xie DY, Sharma SB.  Proanthocyanidins - a final frontier in flavonoid research? New Phytol 2005;165:9-28.

Hostanska K, Nisslein T, Freudenstein F, Reichling J, Saller R.  Evaluation of cell death caused by triterpene glycosides and phenolic substances from Cimicifuga racemosa extract in human MCF-7 breast cancer cells.  Biol Pharm Bull 2004;27(12):1970-1975.

Jazirehi AR, Bonavida B.  Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis.  Mol Can Therap 2004;3(1):71-84.

Keck AS, Finley JW.  Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.  Integ Cancer Therap 2004;3(1):5-12.

Kim YJ, Park HJ, Yoon SH, Kim MJ, Leem KH, Chung JH, Kim HK.  Anticancer effects of oligomeric proanthocyanidins on human colorectal cancer cell line, SNU-C4.  World J Gastroenterol 2005;11(30):4674-4678.

Lamson DW, Brignall MS.  Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.  Alt Med Rev 1999;4(5):304-329.

Lin JK, Tsai SH.  Chemoprevention of cancer and cardiovascular disease by resveratrol.  Proc Natl Sci Counc 1999;23(3):99-106.

Prasad KN.  Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity.  Integrat Cancer Therap 2004;3(4):310-322.

Prasad KN, Kumar B, Yan XD, Hanson AJ, Cole WC.  Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review.  Am J Am Coll Nutr 2003;22(2):108-117.

Singh R, Tyagi AK, Dhanalakshmi S, Agarwal R, Agarwal C.  Grape seed extract inhibits human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.  Int J Cancer 2004;108:733-740.

Szende B, Tyihak E, Kiraly-Veghely Z.  Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures.  Exp Mol Med 2000;32(2):88-92.

Tsuda H, Ohshima Y, Nomoto H, Fujita K, Matsuda E, Iigo M, Takasuka N, Moore MA.  Cancer prevention by natural compounds.  Drug Metab Pharmacokin 2004;19(4):245-263.

Wang ZW, Zhou JM, Huang ZS, Yang AP, Liu ZC, Xia YF, Zeng YX, Zhu XF.  Aloe polysaccharides mediated radioprotective effect through the inhibition of apoptosis.  J Radiat Res 2004;45:447-454.

Waters DJ, Shen S, Cooley DM, Bostwick DG, Qian J, Combs GF, Glickman LT, Oteham C, Schlittler D, Morris JS.  Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate.  J Natl Cancer Inst 2004;95:237-241.

Yamada Y, Nakajima A, Sekihara H.  Anti-apoptotic effect of dehydroepiandrosterone and its role in an aging society.  Int Med 2004;43(2):158-160.

Appetite
Mahendran P, Vanisree AJ, Devi CSS.  The antiulcer activity of Garcinia cambogia extract against indomethacin induced gastric ulcer in rats.  Phytotherap Res 2002;16:80-83.

Arginine
MacKay D.  Nutrients and botanicals for erectile dysfunction: examining the evidence.  Alt Med Rev 2004;9(1):4-16.

MacKay D, Miller AL.  Nutritional support for wound healing.  Altern Med Rev 2003;8(4):359-377.

Neu J, DeMarco V, Li N.  Glutamine: clinical applications and mechanisms of action.  Curr Opin Clin Nutr Metab Care 2002;5:69-75.

Owens G, Balfour D, Biller BMK, Cohen J, Jacobs M, Lease M, Ratnesar R, Schaecher KL, Wilcox DE.  Clinical presentation and diagnosis: growth hormone deficiency in adults.  Am J Manage Care 2004;10(13):S424-S430.

Arrhythmia
Chang Q, Zuo Z, Harrison F, Sum Chow MS.  Hawthorn.  J Clin Pharmacol 2002;42:605-612.

Gaibazzi N, Ziacchi V.  Reversibility of stress-echo induced ST-segment depression by long-term oral n-3 PUFA supplementation in subjects with chest pain syndrome, normal wall motion at stress-echo and normal coronary angiogram.  BMC Cardiovasc Disord 2004;4:1-4.

Hanna J, Chahine R, Aftimas G, Nader G, Nader M, Mounayer A, Esseily F, Chamat S.  Protective effect of taurine against free radicals damage in the rat myocardium.  Exp Toxic Pathol 2004;56:189-194.

Holub BJ.  Clinical nutrition: 4. omega-3 fatty acids in cardiovascular care.  CMAJ 2002;166(5):608-615.

Lewis GRJ.  Should doctors discourage nutritional supplementation? A cardiovascular approach.  Heart Lung Circ 2004;13:245-251.

Zapatero JM.  Selections from current literature: effects of Hawthorn on the cardiovascular system.  Fam Pract 1999;16(5):534-538.

Arsenic
Gupta R, Flora SJS.  Protective value of Aloe vera against some toxic effects of arsenic in rats.  Phytother Res 2005;1923-28.

Arthritis
Braham R, Dawson B, Goodman C.  The effect of glucosamine supplementation on people experiencing regular knee pain.  Br J Sports Med 2003;37:45-49.

Fine AM.  Oligomeric proanthocyanidin complexes:  history, structure, and phytopharmaceutical applications.  Alt Med Rev 2000;5(2):144-151.

Ghosh D, Thejomoorthy P.  Anti-inflammatory and analgesic activities of oleanolic acid 3-/3-glucoside (rdg-1) from Randia dumetorum (rubiaceaea).  Ind J Pharmac 1983;15(4):331-342.

Heaton PR, Reed CF, Mann SJ, Ransley R, Stevenson J, Charlton CJ, Smith BHE, Harper EJ, Rawlings JM.  The role of dietary antioxidants to protect against DNA damage in adult dogs.  J Nutr 2002;132:1720S-1724S.

Horton R.  Vioxx, the implosion of Merck, and aftershocks at the FDA.  Lancet 2004;364(9446):1-2.

Juni P, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M.  Risk of cardiovascular events and rofexcoxib: cumulative meta-analysis.  Lancet 2004;364(9446)1-9.

Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Pournadeali K.  Glucosamine sulfate: a review of efficacy for the pharmacy professional.  Int J Pharm Comp 1999;3(6):428-436.

Sharma S, Thawani V, Hingorani L, Shrivastava M, Bhate VR, Khiyan R.  Pharmacokinetic study of 11-keto B-boswellic acid.  Phytomed 2004;11:255-260.

Shi J, Yu J, Pohorly JE, Kakuda Y.  Polyphyenolics in grape seeds - biochemistry and functionality.  J Med Food 2003;6(4):291-299.

Watkins BA, Li Y, Lippman HE, Seifert MF.  Omega-3 polyunsaturated fatty acids and skeletal health.  Exp Biol Med 2001;226(6):485-497.

Weng-Guang L, Xiao-Yu Z, Yong-Jie W, Xuan T.  Anti-inflammatory effect and mechanism of proanthocyanidins from grape seeds.  Acta Pharmacol Sin 2001;12:1117-1120

Asbestosis
Reiter RJ.  Melatonin: lowering the high price of free radicals.  News Physiol Sci 2000;15:246-250.

Ascites
Aziz MA, Kumar R, Ahmad.  Cancer chemoprevention by resveratrol:  in vitro and in vivo studies and the underlying mechanisms (review).  Int J Oncol 2003;23:17-28.

Aziz MA, Kumar R, Ahmad.  Cancer chemoprevention by resveratrol:  in vitro and in vivo studies and the underlying mechanisms (review).  Int J Oncol 2003;23:17-28.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Ashwagandha (Withania somnifera)
Mishra LC, Singh BB, Dagenais S.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.  Altern Med Rev 2000;5(4):334-346.

Sreemantula S, Nammi S, Kolanukonda R, Koppula S, Boini K.  Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model.  BMC Comp Alt Med 2005;5(1) doi:10.1186/1472-6882-5-1.

Aspartate Aminotransferase (AST)
Can A, Akev N, Ozsov N, Bolkent S, Arda BP, Yanardag R, Okyar A.  Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models.  Biol Pharm Bull 2004;27(5):694-698.

Milliman WB, Lamson DW, Brignall MS.  Hepatitis C: a retrospective study, literature review, and naturopathic protocol.  Alt Med Rev 2000;5(4):355-370.

Aspirin
Araghi-Niknam M, Hosseini S, Larson D, Rohdewald P, Watson RR.  Pine bark extract reduces platelet aggregation.  Int Med 1999;2:73-77.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Watson RR.  Pycnogenol and cardiovascular health.  Evidence-Based Integ Med 2003;1(1):27-32.

Asthenia
Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME.  Nutritional deterioration in cancer: the role of disease and diet.  Clinical Oncology 2003;15:443-450.

Asthma
Barker J, Meletis CD.  Functional foods for childhood development.  Alt Comp Therap 2004;10(3):131-134.

Claustrat B, Brun J, Chazot G.  The basic physiology and pathophysiology of melatonin.  Sleep Med 2005;9:11-24.

Fischer H, Schwarzer C, Illek B.  Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel.  Proc Natl Acad Sci USA 2004;101(10):3691-3696.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Ro JY, Lee BC, Kim JY, Chung YJ, Chung MH, Lee SK, Jo TH, Kim KH, Park YI.  Inhibitory mechanism of aloe single component (alprogren) on mediator release in guinea pig lung mast cells activated with specific antigen-antibody reactions.  J Pharmacol Exp Therap 2000;292(1):114-121.

Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, Tellez-Rojo MM, Moreno-Macias HM, Reyes-Ruiz NL, del Rio-Navarro BE, Ruiz-Navarro MX, Hatch G, Slade R, Hernandez-Avila M.  Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants.  Am J Respir Crit Care Med 2002;166:703-709.

Shaheen SO, Sterne JAC, Thompson RL, Songhurst CE, Margetts BM, Burney PGJ.  Dietary antioxidants and asthma in adults.  Am J Respir Crit Care Med 2001;164:1823-1828.

Atherosclerosis
Abascal K, Yarnell E.  The many faces of Silybum marianum (milk thistle), part 1 - treating cancer and hyperlipidemia and restoring kidney function.  Alt Comp Therapy 2003;9(4):170-175.

Agarwal S, Veketeshwer Rao A.  Tomato lycopene and its role in human health and chronic diseases.  CMAJ 2000;163(6):739-744.

Arruzazabala ML, Menendez MNR, Carbajal RMD, Valdes S, Molina V.  Protective effect of policosanol on atherosclerotic lesions in rabbits with exogenous hypercholesterolemia.  Braz J Med Biol Res 2000;33(7):835-840.

Bova I, Chapman J, Sylantiev C, Korczyn AD, Bornstein NM.  The A677V methylenetetrahydrofolate reductase gene polymorphism and carotid atherosclerosis.  Stroke 1999;30:2180-2182.

Chang Q, Zuo Z, Harrison F, Sum Chow MS.  Hawthorn.  J Clin Pharmacol 2002;42:605-612.

de Gomez Dumm NT, Giammona AM, Touceda LA.  Variations in the lipid profile of patients with chronic reneal failure treated with pyridoxine.  Lipid Health Disease 2003;2(7):1-6.

Droge W.  Free radicals in the physiological control of cell function.  Physiol Rev 2002;82:47-95.

Fernandez S, Mas R, Gamez R, Diaz A, Fernandez J, Orta SD, Illnait J, Castano G, Mendoza S, Valdes F, Alvarez E.  A pharmacological surveillance study of the tolerability of policosanol in the elderly population.  Am J Geriatr Pharmacother 2004;2:219-229.

Fine AM.  Oligomeric proanthocyanidin complexes:  history, structure, and phytopharmaceutical applications.  Alt Med Rev 2000;5(2):144-151.

Hamed SA, Nabeshima T.  The high atherosclerotic risk among epileptics: the atheroprotective role of multivitamins.  J Pharmacol Sci 2005;98:340-353.

Harman D.  The aging process.  Proc Natl Acad Sci 1981;78(11):7124-7128.

Ignatowicz E, Baer-Dubowska W.  Resveratrol, a natural chemopreventive agent against degenerative diseases.  Pol J Pharmacol 2001;53:557-569.

Janikula M.  Policosanol: a new treatment for cardiovascular disease? Alt Med Rev 2002;7(3):203-217.

Jiangang Z, Yuanzhu H, Qi C, Enhui W, Kejiang C, Wu J.  Effects of resveratrol on oxidative modification of human low density lipoprotein.  Chin Med J 2000;113(2):99-102.

Klapcinska B, Derejczyk J, Wieczorowska-Tobis K, Sobczak A, Sadowska-Krepa E, Danch A.  Antioxidant defense in centenarians (a preliminary study).  Acta Bio Pol 2000;47(2):281-292.

Lewis GRJ.  Should doctors discourage nutritional supplementation? A cardiovascular approach.  Heart Lung Circ 2004;13:245-251.

Lin JK, Tsai SH.  Chemoprevention of cancer and cardiovascular disease by resveratrol.  Proc Natl Sci Counc 1999;23(3):99-106.

Mabuchi H, Higashikata T, Kawashiri M, Katsuda S, Mizuno M, Nohara A, Inazu A, Koizumi J, Kobayashi J.  Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.  J Atheroscler Thromb 2005;12:111-119.  

Nakamura Y, Tonogai Y.  Effects of grape seed polyphenols on serum and hepatic lipid contents and fecal steroid excretion in normal and hypercholesterolemic rats.  J Health Sci 2002;48(6):570-578.

Oak MH, El Bedoui J, Schini-Kerth BV.  Antiangiogenic properties of natural polyphenols from red wine and green tea.  J Nutr Biochem 2005;16:1-8.

Rapport L, Lockwood B.  Proanthocyanidins and grape seed extract.  Pharm J 2001;266:581-584.

Sanchez-Moreno C, Cao G, Ou B, Prior RL.  Anthocyanin and proanthocyanidin content in selected white and red wines.  Oxygen radical absorbance capacity comparison with nontraditional wines obtained from highbush blueberry.  J Agric Food Chem 2003;51:4889-4896.

Shi J, Yu J, Pohorly JE, Kakuda Y.  Polyphyenolics in grape seeds - biochemistry and functionality.  J Med Food 2003;6(4):291-299.

Thomas SR, Leichtweis SB, Pettersson K, Croft KD, Mori TA, Brown AJ, Stocker R.  Dietary cosupplementation with vitamin E and coenzyme Q10 inhibits atherosclerosis in apolipoprotein E gene knockout mice.  Arterioscler Thromb Vasc Biol 2001;21:583-593.

Watson RR.  Pycnogenol and cardiovascular health.  Evidence-Based Integ Med 2003;1(1):27-32.

Zapatero JM.  Selections from current literature: effects of Hawthorn on the cardiovascular system.  Fam Pract 1999;16(5):534-538.

Atkins Diet
Lieberman S, Spahrs R, Stanton A, Martinez L, Grinder M.  Weight loss, body measurements, and compliance, a 12-week total lifestyle intervention pilot study.  Alt Comp Therap 2005;11(6):307-318.

Atorvastatin
Mabuchi H, Higashikata T, Kawashiri M, Katsuda S, Mizuno M, Nohara A, Inazu A, Koizumi J, Kobayashi J.  Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.  J Atheroscler Thromb 2005;12:111-119.  

Attention Deficit/Hyperactivity Disorder (AD/HD)
Barker J, Meletis CD.  Functional foods for childhood development.  Alt Comp Therap 2004;10(3):131-134.

Harding KL, Judah RD, Grant CE.  Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD.  Alt Med Rev 2003;8(3):319-330.

Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.

Autism
Ames BN, Elson-Schwab I, Silver EA.  High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity: relevance to genetic disease and polymorphisms.  Am J Clin Nutr 2002;75:616-658.


Kidd PM.  Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management.  Alt Med Rev 2000;5(5):402-428.

Autoimmune Disease
Fawzi WW, Msamanga G, Spiegelman D, Wei R, Kapiga S, Villamor E, Mwakagile D, Mugusi F, Hertzmark E, Essex M, Hunter DJ.  A randomized trial of multivitamin supplements and HIV disease progression and mortality.  N Engl J Med 2004;351:23-32.

Monograph.  Oligomeric Proanthocyanidins (OPCs).  Alt Med Rev 2003;8(4):442-450.